A pregnant patient with a thyroid nodule is generally managed like a nonpregnant woman. However, radioisotopes are contraindicated in pregnancy, so radionuclide scans cannot be performed. Thyroid nodules that are clinically suspicious for malignancy can be aspirated during pregnancy. If the results of cytologic studies are positive for malignancy, a decision must be made whether to recommend surgery during the pregnancy or to postpone it until after delivery. Surgery may be performed relatively safely during the second trimester. Since thyroid cancer is generally indolent in its growth, an alternate strategy could be to defer an FNAB until the postpartum period and to use levothyroxine-suppressive therapy in the meantime to inhibit further growth.